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PostEra Seeks AI Researchers for Drug Discovery Platform
Key points
- PostEra is hiring AI Researchers.
- Role involves developing agentic systems for drug discovery.
- Focus on molecular and tabular in-context learning.
- PostEra has over $1B in AI partnerships.
PostEra's AI-First Approach to Drug Discovery
PostEra operates as an AI-first biotech company, utilizing its AI platform, Proton, to accelerate the discovery of new medicines. The company is advancing an internal pipeline focused on Women's Health and Fertility, having used Proton to nominate clinical candidates in these areas. PostEra also collaborates with pharmaceutical companies on small molecule programs.
Significant Partnerships and Funding
PostEra has secured over $1 billion in AI partnerships, including four multi-year agreements with Pfizer and Amgen. The company also leads an antiviral drug discovery center for pandemic preparedness, funded by a substantial grant from the NIH.
Role of AI Researchers
The AI Researcher role involves developing agentic research verticals at PostEra. This includes using agentic systems to automate the development of mechanistic models for biochemical and physiological processes and analyzing biological data for target validation. Researchers will collaborate with chemists and biologists to apply these models to drug discovery decisions.
Machine Learning Development
Key responsibilities include developing machine learning methods that can adapt to new drug discovery problems with limited labeled data. A particular focus is on molecular and tabular in-context learning, and building foundation models from PostEra’s proprietary multimodal data. The goal is to create models that effectively use drug discovery context, identify relevant prior examples, quantify transfer utility, and provide reliable predictions under distribution shift.
Research Loop and Collaboration
Researchers will drive the full research loop, which encompasses defining tasks, constructing datasets, developing baselines, training and scaling models, performing ablations, and translating successful methods into capabilities for PostEra’s scientists. Prior drug discovery experience is not a prerequisite, but motivation to learn the domain is expected.
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Reporting from
PostEra, an AI-first biotech company, is hiring AI Researchers to develop agentic systems for automating mechanistic models and analyzing biological data in drug discovery. The role focuses on advancing the company's AI platform, Proton, which is used for internal pipelines and partnerships with pharmaceutical companies.